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REP1 Modulates Autophagy and Macropinocytosis to Enhance Cancer Cell Survival

Rab escort protein 1 (REP1), a component of the Rab geranyl-geranyltransferase 2 complex, plays a role in Rab protein recruitment in proper vesicles during vesicle trafficking. In addition to having well-known tissue degenerative phenotypes in the REP1 mutant, REP1 is tightly associated with cancer...

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Detalles Bibliográficos
Autores principales: Choi, Jungwon, Kim, Hyena, Bae, Young Ki, Cheong, Heesun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618515/
https://www.ncbi.nlm.nih.gov/pubmed/28846638
http://dx.doi.org/10.3390/ijms18091866