The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

The deoxyribonucleic acid (DNA) damage response (DDR) is a major feature in the maintenance of genome integrity and in the suppression of tumorigenesis. PALB2 (Partner and Localizer of Breast Cancer 2 (BRCA2)) plays an important role in maintaining genome integrity through its role in the Fanconi an...

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Detalles Bibliográficos
Autores principales: Nepomuceno, Thales C., De Gregoriis, Giuliana, Bastos de Oliveira, Francisco M., Suarez-Kurtz, Guilherme, Monteiro, Alvaro N., Carvalho, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618535/
https://www.ncbi.nlm.nih.gov/pubmed/28858227
http://dx.doi.org/10.3390/ijms18091886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618535/
https://www.ncbi.nlm.nih.gov/pubmed/28858227
http://dx.doi.org/10.3390/ijms18091886

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