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The Role of PALB2 in the DNA Damage Response and Cancer Predisposition
The deoxyribonucleic acid (DNA) damage response (DDR) is a major feature in the maintenance of genome integrity and in the suppression of tumorigenesis. PALB2 (Partner and Localizer of Breast Cancer 2 (BRCA2)) plays an important role in maintaining genome integrity through its role in the Fanconi an...
Autores principales: | Nepomuceno, Thales C., De Gregoriis, Giuliana, Bastos de Oliveira, Francisco M., Suarez-Kurtz, Guilherme, Monteiro, Alvaro N., Carvalho, Marcelo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618535/ https://www.ncbi.nlm.nih.gov/pubmed/28858227 http://dx.doi.org/10.3390/ijms18091886 |
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