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IGF-1 Attenuates Hypoxia-Induced Atrophy but Inhibits Myoglobin Expression in C2C12 Skeletal Muscle Myotubes

Chronic hypoxia is associated with muscle wasting and decreased oxidative capacity. By contrast, training under hypoxia may enhance hypertrophy and increase oxidative capacity as well as oxygen transport to the mitochondria, by increasing myoglobin (Mb) expression. The latter may be a feasible strat...

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Detalles Bibliográficos
Autores principales: Peters, Eva L., van der Linde, Sandra M., Vogel, Ilse S. P., Haroon, Mohammad, Offringa, Carla, de Wit, Gerard M. J., Koolwijk, Pieter, van der Laarse, Willem J., Jaspers, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618538/
https://www.ncbi.nlm.nih.gov/pubmed/28862673
http://dx.doi.org/10.3390/ijms18091889