Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia

Aging is a major factor in the decline of limb blood flow with ischemia. However, the underlying mechanism remains unclear. We investigated the role of mitochondrial reactive oxygen species (ROS) with regard to limb perfusion recovery in aging during ischemia. We performed femoral artery ligation in...

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Detalles Bibliográficos
Autores principales: Miura, Shunsuke, Saitoh, Shu-ichi, Kokubun, Tomoki, Owada, Takashi, Yamauchi, Hiroyuki, Machii, Hirofumi, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618546/
https://www.ncbi.nlm.nih.gov/pubmed/28869535
http://dx.doi.org/10.3390/ijms18091897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618546/
https://www.ncbi.nlm.nih.gov/pubmed/28869535
http://dx.doi.org/10.3390/ijms18091897

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