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The Role of Focal Adhesion Kinase in Keratinocyte Fibrogenic Gene Expression

Abnormal skin scarring causes functional impairment, psychological stress, and high socioeconomic cost. Evidence shows that altered mechanotransduction pathways have been linked to both inflammation and fibrosis, and that focal adhesion kinase (FAK) is a key mediator of these processes. We investiga...

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Detalles Bibliográficos
Autores principales: Januszyk, Michael, Kwon, Sun Hyung, Wong, Victor W., Padmanabhan, Jagannath, Maan, Zeshaan N., Whittam, Alexander J., Major, Melanie R., Gurtner, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618564/
https://www.ncbi.nlm.nih.gov/pubmed/28880199
http://dx.doi.org/10.3390/ijms18091915