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Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges

Umbilical cord blood (UCB) is an attractive alternative to bone marrow for isolation of mesenchymal stem cells (MSCs) to treat articular cartilage defects. Here, we set out to determine the growth factors (bone morphogenetic protein 2 (BMP-2) and transforming growth factor-β (TGF-β1)) and oxygen ten...

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Detalles Bibliográficos
Autores principales: Gómez-Leduc, Tangni, Desancé, Mélanie, Hervieu, Magalie, Legendre, Florence, Ollitrault, David, de Vienne, Claire, Herlicoviez, Michel, Galéra, Philippe, Demoor, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618582/
https://www.ncbi.nlm.nih.gov/pubmed/28885597
http://dx.doi.org/10.3390/ijms18091933