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In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes

Wushanicaritin, a natural polyphenol compound, exerts many biological activities. This study aimed to characterize wushanicaritin glucuronidation by pooled human liver microsomes (HLM), human intestine microsomes and individual uridine diphosphate-glucuronosyltransferase (UGT) enzyme. Glucuronidatio...

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Detalles Bibliográficos
Autores principales: Hong, Xiaodan, Zheng, Yuanru, Qin, Zifei, Wu, Baojian, Dai, Yi, Gao, Hao, Yao, Zhihong, Gonzalez, Frank J., Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618632/
https://www.ncbi.nlm.nih.gov/pubmed/28925930
http://dx.doi.org/10.3390/ijms18091983