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Dual inhibition of BDNF/TrkB and autophagy: a promising therapeutic approach for colorectal cancer

Colorectal cancer (CRC) is the most common digestive cancer in the Western world. Despite effective therapies, resistance and/or recurrence frequently occur. The present study investigated the impact of two survival pathways—neurotrophic factors (TrkB/BDNF) and autophagy—on cell fate and tumour evol...

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Detalles Bibliográficos
Autores principales: Mazouffre, Clément, Geyl, Sophie, Perraud, Aurélie, Blondy, Sabrina, Jauberteau, Marie‐Odile, Mathonnet, Muriel, Verdier, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618676/
https://www.ncbi.nlm.nih.gov/pubmed/28597984
http://dx.doi.org/10.1111/jcmm.13181