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EZH2‐mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis

EZH2, a histone H3 lysine‐27‐specific methyltransferase, is involved in diverse physiological and pathological processes including cell proliferation and differentiation. However, the role of EZH2 in liver fibrosis is largely unknown. In this study, it was identified that EZH2 promoted Wnt pathway‐s...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Chen, Xiao‐xia, Li, Wan‐xia, Wu, Xiao‐qin, Huang, Cheng, Xie, Juan, Zhao, Yu‐xin, Meng, Xiao‐ming, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618695/
https://www.ncbi.nlm.nih.gov/pubmed/28332284
http://dx.doi.org/10.1111/jcmm.13153