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Cyclic peptide *CRRETAWAC* attenuates fibronectin‐induced cytokine secretion of human airway smooth muscle cells by inhibiting FAK and p38 MAPK

α5β1 integrin is highly expressed in airway smooth muscle cells and mediate the adhesion of airway smooth muscle cells to fibronectin to regulate airway remodelling in asthma. This study aimed to investigate the effects of synthetic cyclic peptide *CRRETAWAC* on fibronectin‐induced cytokine secretio...

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Detalles Bibliográficos
Autores principales: Chu, Mengdi, Ji, Jiani, Cao, Wenhao, Zhang, Huojun, Meng, Dan, Xie, Bangruan, Xu, Shuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618697/
https://www.ncbi.nlm.nih.gov/pubmed/28402030
http://dx.doi.org/10.1111/jcmm.13174