Exosomes derived from miR‐181‐5p‐modified adipose‐derived mesenchymal stem cells prevent liver fibrosis via autophagy activation

Proliferating hepatic stellate cells (HSCs) respond to liver damage by secreting collagens that form fibrous scar tissue, which can lead to cirrhosis if in appropriately regulated. Advancement of microRNA (miRNA) hepatic therapies has been hampered by difficulties in delivering miRNA to damaged tiss...

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Detalles Bibliográficos
Autores principales: Qu, Ying, Zhang, Qidi, Cai, Xiaobo, Li, Fei, Ma, Zhenzeng, Xu, Mingyi, Lu, Lungen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618698/
https://www.ncbi.nlm.nih.gov/pubmed/28382720
http://dx.doi.org/10.1111/jcmm.13170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618698/
https://www.ncbi.nlm.nih.gov/pubmed/28382720
http://dx.doi.org/10.1111/jcmm.13170

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