Cargando…

Exosomes derived from miR‐181‐5p‐modified adipose‐derived mesenchymal stem cells prevent liver fibrosis via autophagy activation

Proliferating hepatic stellate cells (HSCs) respond to liver damage by secreting collagens that form fibrous scar tissue, which can lead to cirrhosis if in appropriately regulated. Advancement of microRNA (miRNA) hepatic therapies has been hampered by difficulties in delivering miRNA to damaged tiss...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Ying, Zhang, Qidi, Cai, Xiaobo, Li, Fei, Ma, Zhenzeng, Xu, Mingyi, Lu, Lungen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618698/ https://www.ncbi.nlm.nih.gov/pubmed/28382720 http://dx.doi.org/10.1111/jcmm.13170

Ejemplares similares

Autophagy promotes hepatic differentiation of hepatic progenitor cells by regulating the Wnt/β-catenin signaling pathway
por: Ma, Zhenzeng, et al.
Publicado: (2019)

Y-box Protein-1 Regulates the Expression of Collagen I in Hepatic Progenitor Cells via PDGFR-β/ERK/p90RSK Signalling
por: Li, Fei, et al.
Publicado: (2017)

Analysis of the differential expression of circulating microRNAs during the progression of hepatic fibrosis in patients with chronic hepatitis B virus infection
por: ZHANG, QINGQING, et al.
Publicado: (2015)

CXCL6‐EGFR‐induced Kupffer cells secrete TGF‐β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C‐MYC/EZH2 pathway in liver fibrosis
por: Cai, Xiaobo, et al.
Publicado: (2018)

Exosomes derived from miR-188-3p-modified adipose-derived mesenchymal stem cells protect Parkinson’s disease
por: Li, Qiang, et al.
Publicado: (2021)

Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
por: Lou, Guohua, et al.
Publicado: (2015)

MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates Klebsiella pneumonia Infection-Induced Lung Injury by Targeting STAT3 Signaling
por: Hu, Ren-Jing, et al.
Publicado: (2022)

Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation
por: Li, Xiao, et al.
Publicado: (2016)

The Diagnosis Value of a Novel Model with 5 Circulating miRNAs for Liver Fibrosis in Patients with Chronic Hepatitis B
por: Zhang, Qingqing, et al.
Publicado: (2021)

Exosomes Derived From CircAkap7-Modified Adipose-Derived Mesenchymal Stem Cells Protect Against Cerebral Ischemic Injury
por: Xu, Limin, et al.
Publicado: (2020)

Enhanced renoprotective effect of GDNF-modified adipose-derived mesenchymal stem cells on renal interstitial fibrosis
por: Li, Shulin, et al.
Publicado: (2021)

Exosomal transfer of bone marrow mesenchymal stem cell-derived miR-340 attenuates endometrial fibrosis
por: Xiao, Bang, et al.
Publicado: (2019)

Exosomes derived from miR‐375‐overexpressing human adipose mesenchymal stem cells promote bone regeneration
por: Chen, Si, et al.
Publicado: (2019)

Proteomic Analysis of the Secretome and Exosomes of Feline Adipose-Derived Mesenchymal Stem Cells
por: Villatoro, Antonio J., et al.
Publicado: (2021)

Skeletal Muscle Regeneration by the Exosomes of Adipose Tissue-Derived Mesenchymal Stem Cells
por: Byun, Seong-Eun, et al.
Publicado: (2021)

Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure
por: Wang, Lei, et al.
Publicado: (2023)

Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis
por: Cho, Byong Seung, et al.
Publicado: (2018)

Effects of Exosomes Derived from Adipose-Derived Mesenchymal Stem Cells on Pyroptosis and Regeneration of Injured Liver
por: Piao, Chenxi, et al.
Publicado: (2022)

Adipose Tissue-Derived Mesenchymal Stem Cell-Derived Exosomes Promote Wound Healing and Tissue Regeneration
por: Lee, Jun Ho, et al.
Publicado: (2023)

Mesenchymal Stem Cell Exosomes Derived from Feline Adipose Tissue Enhance the Effects of Anti-Inflammation Compared to Fibroblasts-Derived Exosomes
por: Sung, Soo-Eun, et al.
Publicado: (2021)

MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
por: Lou, Guohua, et al.
Publicado: (2020)

Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25
por: Kuang, Yaoyun, et al.
Publicado: (2020)

Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis
por: Li, Yan, et al.
Publicado: (2021)

Therapeutic potential of adipose-derived mesenchymal stem cell exosomes in tissue-engineered bladders
por: Yang, Tianli, et al.
Publicado: (2021)

Adipose stem cells-derived exosomes modified gelatin sponge promotes bone regeneration
por: Li, Gen, et al.
Publicado: (2023)

The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues
por: Sani, Farnaz, et al.
Publicado: (2023)

Correction to: Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis
por: Li, Yan, et al.
Publicado: (2021)

Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway
por: Chen, Lu, et al.
Publicado: (2020)

Roles of exosomes and exosome-derived miRNAs in pulmonary fibrosis
por: Yang, Yongfeng, et al.
Publicado: (2022)

Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes
por: Katsuda, Takeshi, et al.
Publicado: (2013)

Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells
por: Blazquez, Rebeca, et al.
Publicado: (2014)

Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes
por: Domenis, Rossana, et al.
Publicado: (2018)

Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes
por: Heo, June Seok, et al.
Publicado: (2019)

Antiaging Properties of Exosomes from Adipose-Derived Mesenchymal Stem Cells in Photoaged Rat Skin
por: Liang, Jun-Xian, et al.
Publicado: (2020)

Isolation and identification of exosomes from feline plasma, urine and adipose-derived mesenchymal stem cells
por: Li, Dongsheng, et al.
Publicado: (2021)

Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling
por: Yuan, Ruihong, et al.
Publicado: (2021)

Carcinoma-derived exosomes modify microenvironment
por: Maitland, Norman J.
Publicado: (2015)

MiR‐122 modification enhances the therapeutic efficacy of adipose tissue‐derived mesenchymal stem cells against liver fibrosis
por: Lou, Guohua, et al.
Publicado: (2017)

Exosomes derived from miR-301a-3p-overexpressing adipose-derived mesenchymal stem cells reverse hypoxia-induced erectile dysfunction in rat models
por: Liang, Li, et al.
Publicado: (2021)

The roles and mechanisms of miR-26 derived from exosomes of adipose-derived stem cells in the formation of carotid atherosclerotic plaque
por: Han, Guochao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_enpjj505ko002a42c4v58mf3kt