HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data

BACKGROUND: The human leukocyte antigen (HLA) system is a genomic region involved in regulating the human immune system by encoding cell membrane major histocompatibility complex (MHC) proteins that are responsible for self-recognition. Understanding the variation in this region provides important i...

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Detalles Bibliográficos
Autores principales: Buchkovich, Martin L., Brown, Chad C., Robasky, Kimberly, Chai, Shengjie, Westfall, Sharon, Vincent, Benjamin G., Weimer, Eric T., Powers, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618726/
https://www.ncbi.nlm.nih.gov/pubmed/28954626
http://dx.doi.org/10.1186/s13073-017-0473-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618726/
https://www.ncbi.nlm.nih.gov/pubmed/28954626
http://dx.doi.org/10.1186/s13073-017-0473-6

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