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Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF-κB Pathway

In this study, we demonstrated that temozolomide (TMZ) and propyl gallate (PG) combination enhanced the inhibition of migration in human U87MG glioma cells. PG inhibited the TMZ-induced reactive oxygen species (ROS) generation. The mitochondrial complex III and NADPH oxidase are two critical sites t...

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Detalles Bibliográficos
Autores principales: Yang, Jen-Tsung, Lee, I-Neng, Lu, Fung-Jou, Chung, Chiu-Yen, Lee, Ming-Hsueh, Cheng, Yu-Ching, Chen, Kuo-Tai, Chen, Ching-Hsein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618759/
https://www.ncbi.nlm.nih.gov/pubmed/29062841
http://dx.doi.org/10.1155/2017/9489383