Double quick, double click reversible peptide “stapling”

The development of constrained peptides for inhibition of protein–protein interactions is an emerging strategy in chemical biology and drug discovery. This manuscript introduces a versatile, rapid and reversible approach to constrain peptides in a bioactive helical conformation using BID and RNase S...

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Detalles Bibliográficos
Autores principales: Grison, Claire M., Burslem, George M., Miles, Jennifer A., Pilsl, Ludwig K. A., Yeo, David J., Imani, Zeynab, Warriner, Stuart L., Webb, Michael E., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618791/
https://www.ncbi.nlm.nih.gov/pubmed/28970902
http://dx.doi.org/10.1039/c7sc01342f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618791/
https://www.ncbi.nlm.nih.gov/pubmed/28970902
http://dx.doi.org/10.1039/c7sc01342f

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