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Double quick, double click reversible peptide “stapling”

The development of constrained peptides for inhibition of protein–protein interactions is an emerging strategy in chemical biology and drug discovery. This manuscript introduces a versatile, rapid and reversible approach to constrain peptides in a bioactive helical conformation using BID and RNase S...

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Detalles Bibliográficos
Autores principales:	Grison, Claire M., Burslem, George M., Miles, Jennifer A., Pilsl, Ludwig K. A., Yeo, David J., Imani, Zeynab, Warriner, Stuart L., Webb, Michael E., Wilson, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618791/ https://www.ncbi.nlm.nih.gov/pubmed/28970902 http://dx.doi.org/10.1039/c7sc01342f

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