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A study on the modulation of alpha-synuclein fibrillation by Scutellaria pinnatifida extracts and its neuroprotective properties

Aggregation of alpha-synuclein (α-SN) is a key pathogenic event in Parkinson’s disease (PD) leading to dopaminergic degeneration. The identification of natural compounds inhibiting α-SN aggregation may have a major role in treating PD. Different Scutellaria species are known as valuable medicinal pl...

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Detalles Bibliográficos
Autores principales: Sashourpour, Mahdyeh, Zahri, Saber, Radjabian, Tayebeh, Ruf, Viktoria, Pan-Montojo, Francisco, Morshedi, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619708/
https://www.ncbi.nlm.nih.gov/pubmed/28957336
http://dx.doi.org/10.1371/journal.pone.0184483