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Intranasal post-cardiac arrest treatment with orexin-A facilitates arousal from coma and ameliorates neuroinflammation

Cardiac arrest (CA) entails significant risks of coma resulting in poor neurological and behavioral outcomes after resuscitation. Significant subsequent morbidity and mortality in post-CA patients are largely due to the cerebral and cardiac dysfunction that accompanies prolonged whole-body ischemia...

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Detalles Bibliográficos
Autores principales: Modi, Hiren R., Wang, Qihong, GD, Sahithi, Sherman, David, Greenwald, Elliot, Savonenko, Alena V., Geocadin, Romergryko G., Thakor, Nitish V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619710/
https://www.ncbi.nlm.nih.gov/pubmed/28957432
http://dx.doi.org/10.1371/journal.pone.0182707