Accounting for cell lineage and sex effects in the identification of cell-specific DNA methylation using a Bayesian model selection algorithm

Cell- and sex-specific differences in DNA methylation are major sources of epigenetic variation in whole blood. Heterogeneity attributable to cell type has motivated the identification of cell-specific methylation at the CpG level, however statistical methods for this purpose have been limited to pa...

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Detalles Bibliográficos
Autores principales: White, Nicole, Benton, Miles, Kennedy, Daniel, Fox, Andrew, Griffiths, Lyn, Lea, Rodney, Mengersen, Kerrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619727/
https://www.ncbi.nlm.nih.gov/pubmed/28957352
http://dx.doi.org/10.1371/journal.pone.0182455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619727/
https://www.ncbi.nlm.nih.gov/pubmed/28957352
http://dx.doi.org/10.1371/journal.pone.0182455

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