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Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4

Platelets have a major role in clotting activation and contribute to the innate immune response during systemic infections. Human platelets contain tissue factor (TF) and express functional Toll-like receptor 4 (TLR4). However, the role of TLR4 in triggering the procoagulant properties of platelets,...

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Detalles Bibliográficos
Autores principales: Matus, Valeria, Valenzuela, J. Guillermo, Hidalgo, Patricia, Pozo, L. María, Panes, Olga, Wozniak, Aniela, Mezzano, Diego, Pereira, Jaime, Sáez, Claudia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619753/
https://www.ncbi.nlm.nih.gov/pubmed/28957360
http://dx.doi.org/10.1371/journal.pone.0185431