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Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4
Platelets have a major role in clotting activation and contribute to the innate immune response during systemic infections. Human platelets contain tissue factor (TF) and express functional Toll-like receptor 4 (TLR4). However, the role of TLR4 in triggering the procoagulant properties of platelets,...
Autores principales: | Matus, Valeria, Valenzuela, J. Guillermo, Hidalgo, Patricia, Pozo, L. María, Panes, Olga, Wozniak, Aniela, Mezzano, Diego, Pereira, Jaime, Sáez, Claudia G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619753/ https://www.ncbi.nlm.nih.gov/pubmed/28957360 http://dx.doi.org/10.1371/journal.pone.0185431 |
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