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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers

INTRODUCTION: Variability in red blood cell volumes (distribution width, RDW) increases with age and is strongly predictive of mortality, incident coronary heart disease and cancer. We investigated inherited genetic variation associated with RDW in 116,666 UK Biobank human volunteers. RESULTS: A lar...

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Detalles Bibliográficos
Autores principales: Pilling, Luke C., Atkins, Janice L., Duff, Michael O., Beaumont, Robin N., Jones, Samuel E., Tyrrell, Jessica, Kuo, Chia-Ling, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Murray, Anna, Weedon, Michael N., Harries, Lorna W., Kuchel, George A., Ferrucci, Luigi, Frayling, Timothy M., Melzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771/
https://www.ncbi.nlm.nih.gov/pubmed/28957414
http://dx.doi.org/10.1371/journal.pone.0185083