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High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients

OBJECTIVE: Overall and splice specific expression of Spleen Tyrosine Kinase (SYK) has been posed as a marker predicting both poor and favorable outcome in various epithelial malignancies. However, its role in colorectal cancer is largely unknown. The aim of this study was to explore the prognostic r...

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Detalles Bibliográficos
Autores principales: Coebergh van den Braak, Robert R. J., Sieuwerts, Anieta M., Kandimalla, Raju, Lalmahomed, Zarina S., Bril, Sandra I., van Galen, Anne, Smid, Marcel, Biermann, Katharina, van Krieken, J. Han J. M., Kloosterman, Wigard P., Foekens, John A., Goel, Ajay, Martens, John W. M., IJzermans, Jan N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619807/
https://www.ncbi.nlm.nih.gov/pubmed/28957395
http://dx.doi.org/10.1371/journal.pone.0185607