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A highly-sensitive high throughput assay for dynamin's basal GTPase activity

Clathrin-mediated endocytosis is the major pathway by which cells internalize materials from the external environment. Dynamin, a large multidomain GTPase, is a key regulator of clathrin-mediated endocytosis. It assembles at the necks of invaginated clathrin-coated pits and, through GTP hydrolysis,...

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Detalles Bibliográficos
Autores principales: Mohanakrishnan, Aparna, Tran, Triet Vincent M., Kumar, Meera, Chen, Hong, Posner, Bruce A., Schmid, Sandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619819/
https://www.ncbi.nlm.nih.gov/pubmed/28957392
http://dx.doi.org/10.1371/journal.pone.0185639