Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs

IFITMs are broad antiviral factors that block incoming virions in endosomal vesicles, protecting target cells from infection. In the case of HIV-1, we and others reported the existence of an additional antiviral mechanism through which IFITMs lead to the production of virions of reduced infectivity....

Descripción completa

Detalles Bibliográficos
Autores principales: Tartour, Kevin, Nguyen, Xuan-Nhi, Appourchaux, Romain, Assil, Sonia, Barateau, Véronique, Bloyet, Louis-Marie, Burlaud Gaillard, Julien, Confort, Marie-Pierre, Escudero-Perez, Beatriz, Gruffat, Henri, Hong, Saw See, Moroso, Marie, Reynard, Olivier, Reynard, Stéphanie, Decembre, Elodie, Ftaich, Najate, Rossi, Axel, Wu, Nannan, Arnaud, Frédérick, Baize, Sylvain, Dreux, Marlène, Gerlier, Denis, Paranhos-Baccala, Glaucia, Volchkov, Viktor, Roingeard, Philippe, Cimarelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619827/
https://www.ncbi.nlm.nih.gov/pubmed/28957419
http://dx.doi.org/10.1371/journal.ppat.1006610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619827/
https://www.ncbi.nlm.nih.gov/pubmed/28957419
http://dx.doi.org/10.1371/journal.ppat.1006610

Ejemplares similares