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Mathematical modeling and quantitative analysis of HIV-1 Gag trafficking and polymerization
Gag, as the major structural protein of HIV-1, is necessary for the assembly of the HIV-1 sphere shell. An in-depth understanding of its trafficking and polymerization is important for gaining further insights into the mechanisms of HIV-1 replication and the design of antiviral drugs. We developed a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619834/ https://www.ncbi.nlm.nih.gov/pubmed/28922356 http://dx.doi.org/10.1371/journal.pcbi.1005733 |