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Mathematical modeling and quantitative analysis of HIV-1 Gag trafficking and polymerization

Gag, as the major structural protein of HIV-1, is necessary for the assembly of the HIV-1 sphere shell. An in-depth understanding of its trafficking and polymerization is important for gaining further insights into the mechanisms of HIV-1 replication and the design of antiviral drugs. We developed a...

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Detalles Bibliográficos
Autores principales: Liu, Yuewu, Zou, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619834/
https://www.ncbi.nlm.nih.gov/pubmed/28922356
http://dx.doi.org/10.1371/journal.pcbi.1005733