Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms

Mechanistic differences in the development and function of adaptive, high-affinity antibody-producing B-2 cells and innate-like, “natural” antibody-producing B-1a cells remain poorly understood. Here we show that the multi-functional dynein light chain (DYNLL1/LC8) plays important roles in the estab...

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Detalles Bibliográficos
Autores principales: King, Ashleigh, Li, Lingli, Wong, David M., Liu, Rui, Bamford, Rebecca, Strasser, Andreas, Tarlinton, David M., Heierhorst, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619840/
https://www.ncbi.nlm.nih.gov/pubmed/28922373
http://dx.doi.org/10.1371/journal.pgen.1007010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619840/
https://www.ncbi.nlm.nih.gov/pubmed/28922373
http://dx.doi.org/10.1371/journal.pgen.1007010

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