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Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms

Mechanistic differences in the development and function of adaptive, high-affinity antibody-producing B-2 cells and innate-like, “natural” antibody-producing B-1a cells remain poorly understood. Here we show that the multi-functional dynein light chain (DYNLL1/LC8) plays important roles in the estab...

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Detalles Bibliográficos
Autores principales:	King, Ashleigh, Li, Lingli, Wong, David M., Liu, Rui, Bamford, Rebecca, Strasser, Andreas, Tarlinton, David M., Heierhorst, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619840/ https://www.ncbi.nlm.nih.gov/pubmed/28922373 http://dx.doi.org/10.1371/journal.pgen.1007010

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