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Bone marrow basophils provide survival signals to immature B cells in vitro but are dispensable in vivo

Immature B cells are the first B cell progenitors to express a fully formed B cell receptor and are therefore subject to extensive selection processes that act to mitigate the emergence of autoreactive clones. While it is well appreciated that most B cell generation in the bone marrow is highly depe...

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Detalles Bibliográficos
Autores principales: Moreau, Joshua M., Cen, Selena, Berger, Alexandra, Furlonger, Caren, Paige, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619841/
https://www.ncbi.nlm.nih.gov/pubmed/28957409
http://dx.doi.org/10.1371/journal.pone.0185509