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Bone marrow basophils provide survival signals to immature B cells in vitro but are dispensable in vivo
Immature B cells are the first B cell progenitors to express a fully formed B cell receptor and are therefore subject to extensive selection processes that act to mitigate the emergence of autoreactive clones. While it is well appreciated that most B cell generation in the bone marrow is highly depe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619841/ https://www.ncbi.nlm.nih.gov/pubmed/28957409 http://dx.doi.org/10.1371/journal.pone.0185509 |