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Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin
Single-particle cryogenic electron microscopy (cryo-EM) can now yield near-atomic resolution structures of biological complexes. However, the reference-based alignment algorithms commonly used in cryo-EM suffer from reference bias, limiting their applicability (also known as the ‘Einstein from rando...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619859/ https://www.ncbi.nlm.nih.gov/pubmed/28989723 http://dx.doi.org/10.1107/S2052252517010922 |