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Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities

OBJECTIVE: To investigate genetic variants influencing white matter hyperintensities (WMHs) in the understudied Hispanic population. METHODS: Using 6.8 million single nucleotide polymorphisms (SNPs), we conducted a genome-wide association study (GWAS) to identify SNPs associated with WMH volume (WMH...

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Detalles Bibliográficos
Autores principales: Beecham, Ashley, Dong, Chuanhui, Wright, Clinton B., Dueker, Nicole, Brickman, Adam M., Wang, Liyong, DeCarli, Charles, Blanton, Susan H., Rundek, Tatjana, Mayeux, Richard, Sacco, Ralph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619914/
https://www.ncbi.nlm.nih.gov/pubmed/28975155
http://dx.doi.org/10.1212/NXG.0000000000000185