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lncRNA requirements for mouse acute myeloid leukemia and normal differentiation

A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis and in hematological malignancies. Our analysis of...

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Detalles Bibliográficos
Autores principales: Delás, M Joaquina, Sabin, Leah R, Dolzhenko, Egor, Knott, Simon RV, Munera Maravilla, Ester, Jackson, Benjamin T, Wild, Sophia A, Kovacevic, Tatjana, Stork, Eva Maria, Zhou, Meng, Erard, Nicolas, Lee, Emily, Kelley, David R, Roth, Mareike, Barbosa, Inês AM, Zuber, Johannes, Rinn, John L, Smith, Andrew D, Hannon, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619947/
https://www.ncbi.nlm.nih.gov/pubmed/28875933
http://dx.doi.org/10.7554/eLife.25607