N-acetylcysteine attenuates systemic platelet activation and cerebral vessel thrombosis in diabetes

OBJECTIVE: We previously demonstrated that diabetes exacerbates stroke-induced brain injury, and that this correlates with brain methylglyoxal (MG)-to-glutathione (GSH) status. Cerebral injury was reversed by N-acetylcysteine (NAC). Here we tested if the pro-thrombotic phenotype seen in the systemic...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Yee Aw, Tak, Stokes, Karen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619994/
https://www.ncbi.nlm.nih.gov/pubmed/28961512
http://dx.doi.org/10.1016/j.redox.2017.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619994/
https://www.ncbi.nlm.nih.gov/pubmed/28961512
http://dx.doi.org/10.1016/j.redox.2017.09.005

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