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N-acetylcysteine attenuates systemic platelet activation and cerebral vessel thrombosis in diabetes
OBJECTIVE: We previously demonstrated that diabetes exacerbates stroke-induced brain injury, and that this correlates with brain methylglyoxal (MG)-to-glutathione (GSH) status. Cerebral injury was reversed by N-acetylcysteine (NAC). Here we tested if the pro-thrombotic phenotype seen in the systemic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619994/ https://www.ncbi.nlm.nih.gov/pubmed/28961512 http://dx.doi.org/10.1016/j.redox.2017.09.005 |