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CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma

Subpopulations of nasopharyngeal carcinoma (NPC) contain cells with differential tumourigenic properties. Our study evaluates the tumourigenic potential of CD24, CD44, EpCAM and combination of EpCAM/CD44 cells in NPC. CD44br and EpCAMbr cells enriched for higher S-phase cell content, faster-growing...

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Detalles Bibliográficos
Autores principales: Hoe, Susan Ling Ling, Tan, Lu Ping, Abdul Aziz, Norazlin, Liew, Kitson, Teow, Sin-Yeang, Abdul Razak, Fazlyn Reeny, Chin, Yoon Ming, Mohamed Shahrehan, Nurul Ashikin, Chu, Tai Lin, Mohd Kornain, Noor Kaslina, Peh, Suat-Cheng, Koay, Cheng Eng, Lo, Kwok-Wai, Ahmad, Munirah, Ng, Ching-Ching, Khoo, Alan Soo-Beng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620042/
https://www.ncbi.nlm.nih.gov/pubmed/28959019
http://dx.doi.org/10.1038/s41598-017-12045-8