A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy

Bacteria downregulate their ribosomal activity through dimerization of 70S ribosomes, yielding inactive 100S complexes. In Escherichia coli, dimerization is mediated by the hibernation promotion factor (HPF) and ribosome modulation factor. Here we report the cryo-electron microscopy study on 100S ri...

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Detalles Bibliográficos
Autores principales: Franken, Linda E., Oostergetel, Gert T., Pijning, Tjaard, Puri, Pranav, Arkhipova, Valentina, Boekema, Egbert J., Poolman, Bert, Guskov, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620043/
https://www.ncbi.nlm.nih.gov/pubmed/28959045
http://dx.doi.org/10.1038/s41467-017-00718-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620043/
https://www.ncbi.nlm.nih.gov/pubmed/28959045
http://dx.doi.org/10.1038/s41467-017-00718-x

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