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Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters

Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning...

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Detalles Bibliográficos
Autores principales: Usuki, Fusako, Fujimura, Masatake, Yamashita, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620048/
https://www.ncbi.nlm.nih.gov/pubmed/28959040
http://dx.doi.org/10.1038/s41598-017-09435-3