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Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters
Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning...
Autores principales: | Usuki, Fusako, Fujimura, Masatake, Yamashita, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620048/ https://www.ncbi.nlm.nih.gov/pubmed/28959040 http://dx.doi.org/10.1038/s41598-017-09435-3 |
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