Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice

Cardiac fibrosis is characterized by excessive extracellular matrix deposition that contributes to compromised cardiac function and potentially heart failure. Cardiac pressure overload resulting from trans-aortic constriction in mice leads to cardiac fibrosis and increased Wnt/β-catenin signaling in...

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Detalles Bibliográficos
Autores principales: Xiang, Fu-Li, Fang, Ming, Yutzey, Katherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620049/
https://www.ncbi.nlm.nih.gov/pubmed/28959037
http://dx.doi.org/10.1038/s41467-017-00840-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620049/
https://www.ncbi.nlm.nih.gov/pubmed/28959037
http://dx.doi.org/10.1038/s41467-017-00840-w

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