The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

Calcitonin receptor-like receptor (CLR) and the receptor activity-modifying protein 2 (RAMP2) comprise a receptor for adrenomedullin (AM). Although it is known that AM induces internalization of CLR•RAMP2, little is known about the molecular mechanisms that regulate the trafficking of CLR•RAMP2. Usi...

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Detalles Bibliográficos
Autores principales: Roux, Benoît T., Bauer, Claudia C., McNeish, Alister J., Ward, Stephen G., Cottrell, Graeme S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620052/
https://www.ncbi.nlm.nih.gov/pubmed/28959041
http://dx.doi.org/10.1038/s41598-017-12585-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620052/
https://www.ncbi.nlm.nih.gov/pubmed/28959041
http://dx.doi.org/10.1038/s41598-017-12585-z

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