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Adaptive metabolic rewiring to chronic SFK inhibition

Src family kinases (SFK) are key regulators of cellular proliferation, differentiation, survival, motility and angiogenesis. As such, SFK inhibitors are being tested in clinical trials to prevent metastasis as an alternative to current treatment regimens for a variety of cancers including breast can...

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Detalles Bibliográficos
Autores principales: Pinedo-Carpio, Edgar, Davidson, David, Martinez Marignac, Veronica L., Panasci, Justin, Aloyz, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620134/
https://www.ncbi.nlm.nih.gov/pubmed/28977994
http://dx.doi.org/10.18632/oncotarget.8146