Cargando…
Adaptive metabolic rewiring to chronic SFK inhibition
Src family kinases (SFK) are key regulators of cellular proliferation, differentiation, survival, motility and angiogenesis. As such, SFK inhibitors are being tested in clinical trials to prevent metastasis as an alternative to current treatment regimens for a variety of cancers including breast can...
Autores principales: | Pinedo-Carpio, Edgar, Davidson, David, Martinez Marignac, Veronica L., Panasci, Justin, Aloyz, Raquel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620134/ https://www.ncbi.nlm.nih.gov/pubmed/28977994 http://dx.doi.org/10.18632/oncotarget.8146 |
Ejemplares similares
-
Pharmacological targeting of eIF4E in primary CLL lymphocytes
por: Martinez-Marignac, V, et al.
Publicado: (2013) -
Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming
por: Marignac, Veronica Martinez, et al.
Publicado: (2013) -
Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond
por: Davidson, David, et al.
Publicado: (2013) -
Simultaneous inhibition of ATR and PARP sensitizes colon cancer cell lines to irinotecan
por: Abu-Sanad, Atlal, et al.
Publicado: (2015) -
IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma()
por: Wan, Xiaolin, et al.
Publicado: (2015)