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NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia

NKL homeobox gene MSX1 is physiologically expressed in lymphoid progenitors and subsequently downregulated in developing T- and B-cells. In contrast, elevated expression levels of MSX1 persist in mature natural killer (NK)-cells, indicating a functional role in this compartment. While T-cell acute l...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, MacLeod, Roderick A.F., Drexler, Hans G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620138/
https://www.ncbi.nlm.nih.gov/pubmed/28977998
http://dx.doi.org/10.18632/oncotarget.18609