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Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to...

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Detalles Bibliográficos
Autores principales: Armas-López, Leonel, Piña-Sánchez, Patricia, Arrieta, Oscar, de Alba, Enrique Guzman, Ortiz-Quintero, Blanca, Santillán-Doherty, Patricio, Christiani, David C., Zúñiga, Joaquín, Ávila-Moreno, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620156/
https://www.ncbi.nlm.nih.gov/pubmed/28978016
http://dx.doi.org/10.18632/oncotarget.17715