Enhanced antiproliferative activity of antibody-functionalized polymeric nanoparticles for targeted delivery of anti-miR-21 to HER2 positive gastric cancer

MiR-21 is an oncogenic miR frequently elevated in gastric cancer. Overexpression of miR-21 decreases the sensitivity of gastric cancer cells to trastuzumab, which is a humanized monoclonal antibody targeting human epidermal growth factor receptor 2. However, optimization of miRNA or its anti-miRNA o...

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Detalles Bibliográficos
Autores principales: Wu, Feng-Lei, Zhang, Jian, Li, Wei, Bian, Bao-Xiang, Hong, Yi-Dong, Song, Zi-Yan, Wang, Hui-Yu, Cui, Fang-Bo, Li, Ru-Tian, Liu, Qin, Jiang, Xiao-Dong, Li, Xiao-Min, Zheng, Jun-Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620166/
https://www.ncbi.nlm.nih.gov/pubmed/28978026
http://dx.doi.org/10.18632/oncotarget.18066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620166/
https://www.ncbi.nlm.nih.gov/pubmed/28978026
http://dx.doi.org/10.18632/oncotarget.18066

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