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Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis
Cancer-associated fibroblasts (CAFs) play a pivotal role in the development and progression of many human cancers. Recent studies have shown that Hedgehog (Hh) signalling modulates the stromal microenvironment and prepares a suitable niche for tumour metastasis. However, the detailed molecular mecha...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620175/ https://www.ncbi.nlm.nih.gov/pubmed/28978035 http://dx.doi.org/10.18632/oncotarget.18621 |