Cargando…

Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis

Cancer-associated fibroblasts (CAFs) play a pivotal role in the development and progression of many human cancers. Recent studies have shown that Hedgehog (Hh) signalling modulates the stromal microenvironment and prepares a suitable niche for tumour metastasis. However, the detailed molecular mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Rui, Lv, Mengqin, Li, Fei, Cheng, Teng, Zhang, Zhengzhong, Jiang, Guiying, Zhou, Ying, Gao, Ruiqiu, Wei, Xiao, Lou, Jicheng, Wu, Xizi, Luo, Danfeng, Ma, Xiangyi, Jiang, Jin, Ma, Ding, Xi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620175/
https://www.ncbi.nlm.nih.gov/pubmed/28978035
http://dx.doi.org/10.18632/oncotarget.18621