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Translocation of heme oxygenase-1 contributes to imatinib resistance in chronic myelogenous leukemia
Heme oxygenase-1 (HO-1) degrades heme to bilirubin. In addition, it is upregulated in malignant disease and has been described as an important factor for cancer prognosis and therapy. Under physiological conditions HO-1 is anchored to the endoplasmic reticulum (ER). Under stress conditions HO-1 can...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620182/ https://www.ncbi.nlm.nih.gov/pubmed/28978042 http://dx.doi.org/10.18632/oncotarget.18684 |