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Restoring microenvironmental redox and pH homeostasis inhibits neoplastic cell growth and migration: therapeutic efficacy of esomeprazole plus sulfasalazine on 3-MCA-induced sarcoma

Neoplastic cells live in a stressful context and survive thanks to their ability to overcome stress. Thus, tumor cell responses to stress are potential therapeutic targets. We selected two such responses in melanoma and sarcoma cells: the xc- antioxidant system, that opposes oxidative stress, and su...

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Detalles Bibliográficos
Autores principales: Balza, Enrica, Castellani, Patrizia, Moreno, Paola Sanchez, Piccioli, Patrizia, Medraño-Fernandez, Iria, Semino, Claudia, Rubartelli, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620187/
https://www.ncbi.nlm.nih.gov/pubmed/28978047
http://dx.doi.org/10.18632/oncotarget.18713