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Identification of a novel metastasis inducing lncRNA which suppresses the KAI1/CD82 metastasis suppressor gene and is upregulated in triple-negative breast cancer

Inactivation of tumor/metastasis suppressor genes via epigenetic silencing is a frequent event in human cancers. KAI1/CD82 is a metastasis suppressor gene whose normal protecting activity is deficient in twelve different solid malignancies. Here we have identified and characterized a primarily nucle...

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Detalles Bibliográficos
Autores principales: Aram, Ronni, Dotan, Iris, Hotz-Wagenblatt, Agnes, Canaani, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620192/
https://www.ncbi.nlm.nih.gov/pubmed/28978052
http://dx.doi.org/10.18632/oncotarget.18733